CH 221 - Lab for CH 220

Credit Hours: 1.5

This laboratory course includes: physical procedures; melting point determination; crystallization; distillation; steam distillation; experiments emphasizing basic techniques and procedures; handling organic chemicals; set up and use of organic equipment; safety; separations; purifications; measures of purity; and procedure for disposal of waste chemicals.

Course Outcomes
At the completion of this course, the student should be able to:

demonstrate an awareness of safety practices in the laboratory, and appreciate the historical significance of current technological advances;
measure physical properties of organic structures such as melting and boiling points, index of refraction and density;
name hydrocarbons and other classes of organic compounds in accordance with the IUPAC system;
correctly assemble and use ground glass components;
observe free radical halogenation and measure the quantity and structure of reaction products;
isolate optically active components from natural products using soxhlett and liquid/liquid extractions;
extract alkaloids from natural products and purify by sublimation;
be conversant with the operation and maintenance of vacuum pumps and flash evaporators;
demonstrate the use of cryogenic solids and liquids in the lab;
describe the production and reactions of Grignard reagents;
determine the composition of commercial analgesics through the use of thin layer chromatography;
synthesize and purify components of analgesics by recrystallization; and
compare the effects and relative benefits of both simple and fractional distillation. Learn the use of Raschig rings. Learn computer graphing techniques.

Prerequisites: CH 183
Concurrent Registration: CH 220
F/S (C, N, S)