ML 126 - Bio-Organic Chemistry

Credit Hours: 3

This course introduces the student to the study of organic chemistry which discusses the following topics: alkanes, alkenes, alkynes, aromatic structures, alcohols, aldehydes, ketones, amines, carboxylicacids, anhydrides, esters, and amides. It covers the study of biochemistry of carbohydrates, lipids, proteins, enzymes, and nucleic acids and discusses the nomenclature, structures of molecules, mechanisms of reaction, and metabolic pathways in the body.

Course Outcomes
Upon completion of this course, the student will be able to:

state similarities and differences between organic and biochemistry;
specify and recognize functional groups of alkanes, alkenes, and alkynes;
list and be familiar with naming using IUPAC nomenclature;
write structural formulas for all compounds as stated;
recognize and differentiate substitution, addition oxidation and dehydration reactions in alcohols and oxidation and reduction reactions in aldehydes and ketones, esterification and hydrolysis;
define chirality and identify chiral carbon and stereocenters;
define and discuss properties of enantiomers and stereoisomers;
differentiate D and L monosaccharides from B structures;
differentiate Fischer projection formulas from Haworth projections and structure;
list and explain the major functions of proteins including the 20 amino acids in proteins;
define and discuss enzyme function and specificity and role in diagnosis of disease;
define metabolism and biochemical pathways and its role in energy production and acetyl CoA;
define heredity, storage and expression in DNA;
summarize major difference between DNA and RNA;
describe DNA replication, transcription, translation and protein synthesis; and
define PCR and discuss applications in the clinical lab.

Prerequisites: CH 146 or CH 180, ML 112
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