ML 124 - Serology Lab

• describe the four basic types of immunity: innate, adaptive, humoral and cellular;
• describe the Major Histocompatibility Complex (MHC) and Human Leukocyte Antigens (HLA) and their roles in the immune system;
• describe the various cells involved in the immune response;
• discuss antibody (immunoglobulin) structure and function;
• discuss the mechanisms of the specific immune response;
• discuss the mechanisms of the nonspecific immune response;
• recognize the four types of hypersensitivity reactions;
• discuss the types of autoimmunity and the theories involved;
• discuss and categorize immunodeficiency;
• discuss transplantation and its effects on the immune response;
• discuss the nature of antigens;
• discuss antigen-antibody binding;
• describe the various types of reactions involving precipitation and discuss how they are used;
• describe reactions involving agglutination, inhibition of agglutination and how they are used;
• describe assays using complement;
• describe the immunologic method of immunofluorescence and how it is used;
• describe other serologic testing methods, i.e. polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP), chemiluminescence, NAT, etc.;
• discuss syphilis and other spirochete disease and describe the testing methods used in diagnosis;
• discuss streptococcal serology and describe testing methods used in diagnosis;
• discuss the serology of viral infections: Epstein-Barr, Rubella, Herpes, Hepatitis A, C, D, and E and describe testing methods used for diagnosis;
• discuss Human Immunodeficiency Virus (HIV) serology and describe testing methods used in diagnosis; and
• describe the serologic testing methods used for the diagnosis of autoimmune disease.