CH 222 - Organic Chemistry II

1. interpret infra-red, UV-vis, NMR, and mass spectra, and derive actual structures from these spectra;
2. predict reaction products from the interaction of various reagents with acids, aldehydes, ketones, ethers, amines, heterocycles, amino acids and proteins, glycols and diazonium salts;
3. name the classes of organic compounds in accordance with the IUPAC system;
4. describe the mechanism of Aldol and Claissen condensations;
5. predict relative energies of molecular orbitals and demonstrate an understanding of LCAO-MO theory, including HOMO and LUMO concepts and constraints, especially in the production of commercial dyestuffs;
6. use radioactive tracers to elucidate mechanisms such as esterification;
7. describe the synthetic production of natural products and their subsequent use in the creation of more esoteric molecules;
8. be conversant with the competing mechanisms of nucleophilic substitution as applied to more sophisticated systems;
9. predict the relative acidity (basicity) of carboxylic acids, alcohols, phenols, and amines;
10. describe the production and properties of polymers, including isotactic, syndiotactic, and atactic conformations;
11. predict products from Hoffmann Degradation;
12. compare and contrast the relative strengths of various oxidative and reductive reagents; and
13. propose good synthetic routes to all of the above functional groups and families.